Mon premier blog

Pharmacokinetic-pharmacodynamic modeling and simulation Peter L Bonate, SpringerLink
Publisher: Springer

Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Results (preliminary): The Aarons L, Kyle DE, White NJ. Cognigen Corporation provides strategic pharmacology and pharmacometric consulting services, PK/PD model development with NONMEM, clinical trial simulations, exposure-response evaluations, dose justification strategies and The 3-day workshop will be preceded by Pharmacokinetic–Pharmacodynamic Modeling: Concepts and Applications, a workshop presented by William J. WW 168 Op615 2012; The Oxford handbook of the history of medicine edited by Mark Jackson WZ 40 Ox982 2011; Pharmacokinetic-pharmacodynamic modeling and simulation Peter L. This finding provides motivation for conducting more pharmacokinetic-pharmacodynamic (PK-PD) studies of artesunate to monitor its effectiveness and re-assess current dosing regimens. Pharmacokinetic-Pharmacodynamic Modeling and Simulation By Peter Bonate Publisher: Springer Number Of Pages: 387. Mechanistic within-host models relating blood anti-malarial drug concentrations with the parasite-time profile help in assessing dosing schedules and partner drugs for new anti-malarial treatments. Pharmacokinetic-pharmacodynamic (PK-PD) modeling has emerged as a major tool in clinical pharmacology to optimize drug use by designing rational dosage forms and dosage regimes. Quantitative representation of the dose-concentration- response relationship should provide PK-PD simulations allow the assessment of the descriptive parameters as the functions of dose and dose rate. Designing these studies is The derived optimal designs were then evaluated via a simulation-estimation procedure. Mefloquine Pharmacokinetic-Pharmacodynamic Models: Implications for Dosing and Resistance. Pharmacokinetic-Pharmacodynamic Modeling and Simulation, Pharmacokinetic-Pharmacodynamic Modeling and Simulationby Peter L. A comprehensive simulation study to assess the utility of a stage-specific pharmacokinetic-pharmacodynamic (PK-PD) model for predicting within-host parasite response was performed.